Our Work
Nuclear export of circular RNA
Nature, 627, 212–220 (2024)
LH Ngo, AG Bert, BK Dredge, T Williams, W Li, KT Carey … JA Chao, GJ Goodall* and VO Wickramasinghe*
Pathogenic variants in nucleoporin TPR cause severe intellectual disability in humans
Human Molecular Genetics, 31(3):362-375 (2022)
NJ Van Bergen, KM Bell, K Carey.... VO Wickramasinghe*, SM White* and J Christodoulou*
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RNA in cancer
Nature Reviews Cancer. 21(1):22-36 (2021) - Cover Image
GJ Goodall* and VO Wickramasinghe*
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Germline heterozygous mutations in Nxf1 perturb RNA metabolism and trigger thrombocytopenia and lymphopenia in mice
Blood Advances, 4 (7): 1270-1283. (2020)
S Chappaz, CW Law, MR Dowling, KT Carey, RM Lane, LH Ngo, VO Wickramasinghe, GK Smyth, ME Ritchie, BT Kile.
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A systems view of spliceosomal assembly and branchpoints with iCLIP
Nature Structural Molecular Biology 26(10):930-940 (2019)
M Briese, N Haberman, CR Sibley, R Faraway, AS Elser, AM Chakrabarti, Z Wang, J Konig, D Perera, VO Wickramasinghe, AR Venkitaraman, NM Luscombe, L Saieva, L Pellizzoni, CWJ Smith, T Curk and J Ule.
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Regulatory potential of the RNA processing machinery: Implications for human disease
Trends in Genetics 34 (4): 279-290. (2018)
KT Carey and VO Wickramasinghe*
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Nuclear export of RNA: Different sizes, shapes and functions
Seminars in Cell and Developmental Biology (17) 30059-9 (2017)
T Williams, LH Ngo and VO Wickramasinghe*
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Impact of alternative splicing on the human proteome
Cell Reports 20: 1229-1241 (2017) Research Highlight at Nature Methods
Y Liu, M Gonzàlez-Porta, S Santos, A Brazma, JC Marioni, R Aebersold*, AR Venkitaraman* and VO Wickramasinghe*
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RNA processing and genome stability: cause and consequence.
Molecular Cell 61 (4): 496-505. (2016)
VO Wickramasinghe* and AR Venkitaraman*
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Control of mammalian gene expression by selective mRNA export
Nature Reviews Molecular Cell Biology, 16 (7): 431-42 (2015)
VO Wickramasinghe* and RA Laskey*
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